ligand recognition at the human leukotriene B4 receptor 1

Structural insights on ligand recognition on the human leukotriene B4 receptor 1

The leukotriene B4 receptor 1 (BLT1) regulates the recruitment and chemotaxis of various cell sorts and performs a job within the pathophysiology of infectious, allergic, metabolic, and tumorigenic human illnesses. Right here we current a crystal construction of human BLT1 (hBLT1) in advanced with a selective antagonist MK-D-046, developed for the therapy of sort 2 diabetes and different inflammatory circumstances.

Complete evaluation of the construction and structure-activity relationship information, bolstered by site-directed mutagenesis and docking research, reveals molecular determinants of ligand binding and selectivity towards completely different BLT receptor subtypes and throughout species.

The construction helps to determine a putative membrane-buried ligand entry channel in addition to potential receptor binding modes of endogenous agonists. These structural insights of hBLT1 enrich our understanding of its ligand recognition and open up future avenues in structure-based drug design.

Reverse alterations of 5-HT _2A receptor mind density in topics with schizophrenia: relevance of radiotracers pharmacological profile

The standing of serotonin 5-HT_2A receptors (5-HT_2ARs) in schizophrenia has been controversial. In vivo positron emission tomography neuroimaging and in vitro autopsy binding research have reported conflicting outcomes about 5-HT_2AR density. Radiotracers bind completely different receptor conformations relying on their agonist, antagonist or inverse agonist properties.

This research investigates 5-HT_2AR density within the autopsy prefrontal cortex from topics with schizophrenia and controls utilizing three radiotracers with a unique pharmacological profile.

The particular binding parameters of the inverse agonist [¹⁸F]altanserin, the agonist [³H]lysergic acid diethylamide (LSD) and the antagonist [³H]MDL100907 to mind cortex membranes from 20 topics with schizophrenia and 20 individually matched controls had been evaluated below related methodological circumstances.

Ten schizophrenia topics had been antipsychotic-free at dying. Saturation curve analyses had been carried out by non-linear regression to acquire a maximal density of binding websites (B_max) and the affinity of the respective radiotracers (Okay_d).

In schizophrenia topics, 5-HT_2AR density was decreased when quantified by [¹⁸F]altanserin binding, whereas elevated when evaluated by [³H]LSD binding. Nevertheless, [³H]MDL100907 binding was unaltered.

A slight lack of affinity (greater Okay_d) was noticed solely in [³H]LSD binding. The findings had been extra evident in antipsychotic-free topics than in antipsychotic-treated topics. In conclusion, a better proportion of the 5-HT_2AR-active practical conformation, which is slightly recognized by agonist radiotracers, was noticed in schizophrenia sufferers.

A consequent discount of the inactive 5-HT_2AR conformation, which is preferentially recognized by inverse agonist radiotracers, was additionally obtained. Antagonist radiotracers don’t distinguish between molecular conformations of the receptor, and accordingly, the absence of adjustments was proven. These outcomes are suitable with the proposed elevated practical exercise of mind cortical 5-HT_2ARs in schizophrenia.

κ-opioid receptor stimulation alleviates rat vascular easy muscle cell calcification through PFKFB3-lactate signaling

Within the current research, the results and mechanism of motion of U50,488H (a selective κ-opioid receptor agonist) on calcification of rat vascular easy muscle cells (VSMCs) induced by β-glycerophosphate (β-GP) had been investigated.

VSMCs had been remoted and cultured in conventional FBS-based media. A calcification mannequin was established in VSMCs below hyperphosphatemia and intracellular calcium contents. Alkaline phosphatase (ALP), lactate dehydrogenase (LDH), and lactate had been detected in cell tradition supernatants earlier than and after therapy. Alizarin pink staining was used to detect the diploma of calcification of VSMCs.

Expression ranges of key molecules of osteogenic markers, fructose-2,6-biphosphatase 3 (PFKFB3), and proline hydroxylase 2 (PHD2), had been decided utilizing western blotting. Additional, vascular calcification was induced by vitamin D3 plus nicotine in rats and remoted thoracic aortas, calcium focus was assessed in rat aortic rings in vitro.

We demonstrated that U50,488H inhibited VSMC calcification in a concentration-dependent method. Furthermore, U50,488H considerably inhibited osteogenic differentiation and ALP exercise in VSMCs pretreated with β-GP. Additional research confirmed that PFKFB3 expression, LDH stage, and lactate content material considerably elevated throughout calcification of VSMCs; U50,488H reversed these adjustments.

PHD2 expression confirmed the other development in comparison with PFKFB3 expression. nor-BNI or 3-PO abolished U50,488H protecting results. In addition to, U50,488H inhibited VSMC calcification in rat aortic rings ex vivo. Collectively, our experiments present that κ-opioid receptor activation inhibits VSMC calcification by decreasing PFKFB3 expression and lactate content material, offering a possible drug goal and technique for the scientific therapy of vascular calcification.

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BSA-drug-ZnO-PEI conjugates interplay with glycans of gp60 endothelial cell receptor protein for focused drug supply: a complete spectroscopic research

The zinc oxide (ZnO) nanoparticles (NPs) have a number of biomedical purposes corresponding to drug supply, bio-imaging, and biomedical analysis. ZnO NPs had been remedied with polyethyleneimine (PEI) and modified with bovine serum albumin (BSA). Two anticancer medication – Cisplatin (CIS) and Gemcitabine (GEM) had been utilized in conjugation with BSA.

BSA-ZnO-PEI (conjugate 1), BSA-CIS-ZnO-PEI (conjugate 2), and BSA-GEM-ZnO-PEI (conjugate 3) can be utilized for focused drug supply through glycans – N-acetylneuraminic acid (NANA), L-fucose (FUC), N-acetyl glucosamine (NAG), D-mannose (MAN), and D-galactose (GAL), of albumin binding membrane receptor protein (gp60). Appreciable interplay and the sturdy binding of conjugate 2 and conjugate Three with NANA had been noticed by UV-visible absorption and fluorescence spectra.

The electrostatic stability of conjugate 2 and conjugate Three with NANA was significantly elevated compared to conjugate 1 as evident with zeta potential values. The fluorescence quenching information (Ksv and kq) and binding parameters (Okay and n) of BSA-CIS, BSA-GEM, conjugate 2, and conjugate Three with NANA and FUC attributes to the sturdy binding.

Amide I and amide III bands of the Raman sign urged insignificant loss in alpha-helical and beta-sheet content material of conjugate 2 and conjugate Three with NANA and FUC. Due to this fact, the current research goes to help within the complete growth of conjugates for focused drug supply based mostly on the differential glycation sample of gp60 protein.Communicated by Ramaswamy H. Sarma.

EC MEDIUM
E05-100-10kg	Alphabiosciences	10 kg	EUR 976.8

EC MEDIUM
E05-100-2Kg	Alphabiosciences	2 Kg	EUR 259.2

EC MEDIUM
E05-100-500g	Alphabiosciences	500 g	EUR 114

OF Medium
MED1664	Scientific Laboratory Supplies	500G	EUR 79.2

M9 Medium
SD7024	Bio Basic	250g	EUR 86.1

YM Medium
SD7031	Bio Basic	250g	EUR 84.54

HLP MEDIUM
H08-107-10kg	Alphabiosciences	10 kg	EUR 2733.6

HLP MEDIUM
H08-107-2Kg	Alphabiosciences	2 Kg	EUR 640.8

HLP MEDIUM
H08-107-500g	Alphabiosciences	500 g	EUR 218.4

M63 Medium
SD7033	Bio Basic	250g	EUR 86.1

SIM MEDIUM
S19-110-10kg	Alphabiosciences	10 kg	EUR 1225.2

SIM MEDIUM
S19-110-2kg	Alphabiosciences	2kg	EUR 313.2

SIM MEDIUM
S19-110-500g	Alphabiosciences	500 g	EUR 128.4

SOB MEDIUM
S19-124-10kg	Alphabiosciences	10 kg	EUR 1158

SOB MEDIUM
S19-124-2kg	Alphabiosciences	2kg	EUR 298.8

SOB MEDIUM
S19-124-500g	Alphabiosciences	500 g	EUR 124.8

Ec Medium 500gm
231430	Scientific Laboratory Supplies	EACH	EUR 176.4

TCBS Medium
MED1188	Scientific Laboratory Supplies	PK10	EUR 9.6

M9CA Medium
SD7025	Bio Basic	250g	EUR 86.1

Sob Medium 500gm
244310	Scientific Laboratory Supplies	EACH	EUR 261.6

Rat Cartilage Growth Medium PrimaCell: Normal Articular Cartilage Growth Medium
9-25023	CHI Scientific	5 x 100 ml	Ask for price

DNase Medium
MED1196	Scientific Laboratory Supplies	PK10	EUR 10.8

TYGPN Medium
SD7032	Bio Basic	250g	EUR 84.01

Heller's Medium
CP014-010	GenDepot	10X1L	EUR 118.8

Heller's Medium
CP014-500	GenDepot	50L	EUR 151.2

Human Cartilage Growth Medium PrimaCell: Normal Articular Cartilage Growth Medium
9-46043	CHI Scientific	5 x 100 ml	Ask for price

Insect Cell Medium: TNM-FH Insect Culture Medium
ABP-MED-10001	Allele Biotech	1 liter	Ask for price

Mounting Medium
4300	Virostat	3 ml	EUR 216.6
Description: This is Mounting medium (non-fading) used for maintaining optimal conditions needed to obtain the maximum fluorescence emission from Fluorescein.

Advanced Medium
C0003-04	Addexbio	RT 500 mL Bottle	EUR 123.6

COLIFORM MEDIUM
C03-127-10kg	Alphabiosciences	10 kg	EUR 1588.8

COLIFORM MEDIUM
C03-127-2kg	Alphabiosciences	2kg	EUR 392.4

COLIFORM MEDIUM
C03-127-500g	Alphabiosciences	500 g	EUR 150

Hoagland's Medium
CP015-010	GenDepot	10X1L	EUR 118.8

Hoagland's Medium
CP015-500	GenDepot	50L	EUR 151.2

Insect Cell Medium: Serum-Free Insect Culture Medium
ABP-MED-10002	Allele Biotech	1 liter	Ask for price

RPMI 1640 Medium
abx098879-500ml	Abbexa	500 ml	EUR 210

A-1 MEDIUM
A01-116-10kg	Alphabiosciences	10 kg	EUR 1240.8

A-1 MEDIUM
A01-116-2Kg	Alphabiosciences	2 Kg	EUR 316.8

A-1 MEDIUM
A01-116-500g	Alphabiosciences	500 g	EUR 129.6

MCDB 131 Medium
CM034-050	GenDepot	500ml	EUR 102

MCDB 131 Medium
CM034-300	GenDepot	6x500ml	EUR 198

MCDB 131 Medium
CM034-310	GenDepot	10x500ml	EUR 262.8

MCDB 131 Medium
CM034-320	GenDepot	20x500ml	EUR 408

MCDB 131 Medium
CM034-350	GenDepot	50x500ml	EUR 702

Medium 199/BCDB 105
C0012-02	Addexbio	RT 500 mL Bottle	EUR 181.2

Insect Cell Medium: Grace?s Insect Medium (Unsupplemented)
ABP-MED-10004	Allele Biotech	1 liter	Ask for price

Isp Medium 2 500gm
277010	Scientific Laboratory Supplies	EACH	EUR 356.4

Isp Medium 4 500gm
277210	Scientific Laboratory Supplies	EACH	EUR 340.8

BPS Medium 1
79259	BPS Bioscience	100 ml	EUR 120
Description: This liquid BPS Medium is optimized for use with many BPS Reporter Kits including_x000D_ • 60612: AP1 Reporter Kit (JNK Pathway)_x000D_ • 60514: ARE Reporter Kit (Nrf2 Antioxidant Pathway)_x000D_ • 60611: CRE/CREB Reporter Kit (cAMP/PKA Signaling Pathway)_x000D_ • 60614: NF-κB Reporter Kit (NF-κB Signaling Pathway)_x000D_ • 60509: Notch1/CSL Reporter Kit (Notch Signaling Pathway)_x000D_ • 60654: SBE Reporter Kit (TGFβ/SMAD signaling pathway)_x000D_ • 60511: SRE Reporter Kit (MAPK/ERK Signaling Pathway)_x000D_ • 60500: TCF/LEF Reporter Kit (Wnt Signaling Pathway)

BPS Medium 7
79260	BPS Bioscience	100 ml	EUR 120
Description: This liquid BPS Medium is optimized for use with select BPS reporter kits.

BPS Medium 8
79385	BPS Bioscience	100 ml	EUR 120
Description: This liquid BPS Medium is optimized for use with the CSF1R/SRE Reporter Kit (BPS Bioscience, #79379).

Thaw Medium 4
60181-1	BPS Bioscience	100 ml	EUR 140
Description: This liquid Cell Thawing Medium is optimized for thawing and plating select BPS Bioscience cell lines, including• CFTR - HEK 293 Recombinant Cell Line #60506• Nav1.8/β2 - HEK293 Recombinant Cell Line #60521• NaV1.7-HEK293 Recombinant Cell Line #60607

Thaw Medium 4
60181-2	BPS Bioscience	500 ml	EUR 600
Description: This liquid Cell Thawing Medium is optimized for thawing and plating select BPS Bioscience cell lines, including• CFTR - HEK 293 Recombinant Cell Line #60506• Nav1.8/β2 - HEK293 Recombinant Cell Line #60521• NaV1.7-HEK293 Recombinant Cell Line #60607

Thaw Medium 5
60182-1	BPS Bioscience	100 ml	EUR 140
Description: This liquid Cell Thawing Medium is optimized for thawing and plating select BPS Bioscience cell lines, including• Gli Reporter - NIH3T3 Recombinant Cell line (Hedgehog Pathway) #60409

Thaw Medium 5
60182-2	BPS Bioscience	500 ml	EUR 600
Description: This liquid Cell Thawing Medium is optimized for thawing and plating select BPS Bioscience cell lines, including• Gli Reporter - NIH3T3 Recombinant Cell line (Hedgehog Pathway) #60409

Thaw Medium 6
60183-1	BPS Bioscience	100 ml	EUR 140
Description: This liquid Cell Thawing Medium is optimized for thawing and plating select BPS Bioscience cell lines, including• Myc Reporter (Luc) - HCT116 Recombinant Cell Line (Myc Signaling Pathway) #60520• NF-κB Reporter (Luc) - HCT116 Recombinant Cell Line #60623 • RARα Reporter - HEK293 Recombinant Cell Line #60503 • RARβ Reporter - HEK293 Recombinant Cell Line #60603 • RARγ Reporter - HEK293 Reporter Cell Line #60604

Thaw Medium 6
60183-2	BPS Bioscience	500 ml	EUR 600
Description: This liquid Cell Thawing Medium is optimized for thawing and plating select BPS Bioscience cell lines, including• Myc Reporter (Luc) - HCT116 Recombinant Cell Line (Myc Signaling Pathway) #60520• NF-κB Reporter (Luc) - HCT116 Recombinant Cell Line #60623 • RARα Reporter - HEK293 Recombinant Cell Line #60503 • RARβ Reporter - HEK293 Recombinant Cell Line #60603 • RARγ Reporter - HEK293 Reporter Cell Line #60604

Thaw Medium 2
60184-1	BPS Bioscience	100 ml	EUR 150
Description: This liquid Cell Thawing Medium is optimized for thawing and plating BPS Bioscience's Jurkat-based cell lines, including• PD-1/NFAT Reporter-Jurkat cell #60535• NFAT Reporter (Luc) - Jurkat Cell Line #60621• NF-κB-Luciferase Reporter (Luc) - Jurkat Cell Line #60651• ADCC Bioassay Effector Cell F variant (Low Affinity) #60540• ADCC Bioassay Effector Cell V variant (High Affinity) #60541Note: once cells are well-established, switch to the appropriate cell growth medium.

Thaw Medium 2
60184-2	BPS Bioscience	500 ml	EUR 675
Description: This liquid Cell Thawing Medium is optimized for thawing and plating select BPS Bioscience cell lines, including_x000D__x000D_• PD-1/NFAT Reporter-Jurkat cell #60535_x000D__x000D_• NFAT Reporter (Luc) - Jurkat Cell Line #60621_x000D__x000D_• NF-Ä¸B-Luciferase Reporter (Luc) - Jurkat Cell Line #60651_x000D__x000D_• ADCC Bioassay Effector Cell F variant (Low Affinity) #60540_x000D__x000D_• ADCC Bioassay Effector Cell V variant (High Affinity) #60541_x000D__x000D_Note: once cells are well-established, switch to the appropriate cell growth medium.

Thaw Medium 7
60185-1	BPS Bioscience	100 ml	EUR 140
Description: This liquid Cell Thawing Medium is optimized for thawing and plating select BPS Bioscience cell lines, including• Myc Reporter (Luc) - HCT116 Recombinant Cell Line (Myc Signaling Pathway) #60520 • NF-κB Reporter (Luc) - HCT116 Recombinant Cell Line #60623

Thaw Medium 7
60185-2	BPS Bioscience	500 ml	EUR 600
Description: This liquid Cell Thawing Medium is optimized for thawing and plating select BPS Bioscience recombinant cell lines, including • Myc Reporter (Luc) - HCT116 Recombinant Cell Line (Myc Signaling Pathway) #60520 • NF-κB Reporter (Luc) - HCT116 Recombinant Cell Line #60623

Thaw Medium 3
60186-1	BPS Bioscience	100 ml	EUR 150
Description: This liquid Cell Thaw Medium is optimized for thawing and plating BPS Bioscience's CHO cell-based recombinant cell lines, including• TCR Activator - CHO Recombinant Cell line #60539 • TCR activator / PD-L1 - CHO Recombinant Cell line #60536 It is designed for use in a 37°C incubator with an atmosphere of 5% CO2/95% air. Note: once cells are well established, switch to an appropriate cell growth medium.

Thaw Medium 3
60186-2	BPS Bioscience	500 ml	EUR 645
Description: This liquid thaw medium is optimized for thawing and plating select BPS Bioscience recombinant cell lines, including_x000D__x000D_• TCR Activator - CHO Recombinant Cell line #60539 _x000D_• TCR activator / PD-L1 - CHO Recombinant Cell line #60536 _x000D__x000D_• CD27 CHO-K1 Stable Recombiant Cell Line #60624 _x000D__x000D_• PD-L1 - CHO Recombinant Cell Line #60543 _x000D__x000D_• NF-κB Reporter (Luc) - CHO-K1 Recombinant Cell Line #60622_x000D_• CD137L (4-1BBL) CHO-K1 Recombinant Cell Line #60523_x000D__x000D_It is designed for use in a 37°C incubator with an atmosphere of 5% CO2/95% air. _x000D_Note: once cells are well established, switch to an appropriate cell growth medium._x000D_

Thaw Medium 1
60187-1	BPS Bioscience	100 ml	EUR 155
Description: This liquid HEK293 Cell Thawing Medium is optimized for thawing and plating BPS Bioscience's HEK293 recombinant cell lines.

Thaw Medium 1
60187-2	BPS Bioscience	500 ml	EUR 695
Description: This liquid Thaw Medium is optimized for thawing and plating BPS Bioscience's HEK293 recombinant cell lines.

10mL S.O.C. Medium
46-003-CR	Scientific Laboratory Supplies	PK10	EUR 122.4

Thaw Medium 12
78074-1	BPS Bioscience	100 ml	EUR 140
Description: This liquid Cell Thawing Medium is optimized for thawing and plating select BPS Bioscience recombinant cell lines, including: • Cas9-expressing MDA-MB-231 cells (BPS Bioscience #78069)

Thaw Medium 12
78074-2	BPS Bioscience	500 ml	EUR 600
Description: This liquid Cell Thawing Medium is optimized for thawing and plating select BPS Bioscience recombinant cell lines, including: • Cas9-expressing MDA-MB-231 cells (BPS Bioscience #78069)

Thaw Medium 14
78397-1	BPS Bioscience	100 ml	EUR 140
Description: This liquid Cell Thawing Medium is optimized for thawing and plating select BPS Bioscience recombinant cell lines.

Thaw Medium 14
78397-2	BPS Bioscience	500 ml	EUR 600
Description: This liquid Cell Thawing Medium is optimized for thawing and plating select BPS Bioscience recombinant cell lines.

Thaw Medium 8
79652-1	BPS Bioscience	100 ml	EUR 140
Description: This liquid Cell Thawing Medium is optimized for thawing and plating select BPS Bioscience recombinant cell lines including NF- κB Reporter (Luc) – THP-1 Cell Line, #79645

Thaw Medium 8
79652-2	BPS Bioscience	500 ml	EUR 600
Description: This liquid Cell Thawing Medium is optimized for thawing and plating select BPS Bioscience recombinant cell lines including NF- κB Reporter (Luc) – THP-1 Cell Line, #79645

Thaw Medium 9
79665-1	BPS Bioscience	100 ml	EUR 140
Description: This liquid Cell Thawing Medium is optimized for thawing and plating select BPS Bioscience cell lines, including_x000D_• CRE/CREB Reporter Lentivirus #79580 _x000D_• NF-κB Reporter Luciferase Reporter Lentivirus #79564

Thaw Medium 9
79665-2	BPS Bioscience	500 ml	EUR 600
Description: This liquid Cell Thawing Medium is optimized for thawing and plating select BPS Bioscience cell lines, using • CRE/CREB Reporter Lentivirus #79580 _x000D_• NF-κB Reporter Luciferase Reporter Lentivirus #79564

Thaw Medium 10
79704-1	BPS Bioscience	100 ml	EUR 140
Description: This liquid medium is optimized to culture select BPS Bioscience cell lines.

Thaw Medium 10
79704-2	BPS Bioscience	500 ml	EUR 600
Description: This liquid medium is optimized to culture select BPS Bioscience cell lines.

Thaw Medium 11
79976-1	BPS Bioscience	100 ml	EUR 140
Description: This liquid medium is optimized to culture select BPS Bioscience cell lines._x000D_Optimized for Use With:_x000D_NF- κB Reporter (Luc) - Raw 264.7 Cell line (BPS Bioscience 79978)

Thaw Medium 11
79976-2	BPS Bioscience	500 ml	EUR 600
Description: This liquid medium is optimized to culture select BPS Bioscience cell lines._x000D_Optimized for Use With:_x000D_NF- κB Reporter (Luc) - Raw 264.7 Cell line (BPS Bioscience 79978)

Thaw Medium 15
78412-1	BPS Bioscience	100 ml	EUR 140
Description: This liquid Cell Thawing Medium is optimized for thawing and plating select BPS Bioscience recombinant cell lines.

Thaw Medium 15
78412-2	BPS Bioscience	500 ml	EUR 600
Description: This liquid Cell Thawing Medium is optimized for thawing and plating select BPS Bioscience recombinant cell lines.

Thaw Medium 16
78647-1	BPS Bioscience	100 ml	EUR 140
Description: This liquid Cell Thawing Medium is optimized for use with tetracycline-inducible system.

Thaw Medium 16
78647-2	BPS Bioscience	500 ml	EUR 600
Description: This liquid Cell Thawing Medium is optimized for use with tetracycline-inducible system.

Of Basal Medium 500gm
268820	Scientific Laboratory Supplies	EACH	EUR 224.4

Medium 199 (Mod) Powder
90-050PB	Scientific Laboratory Supplies	EACH	EUR 93.48

Assay Medium 1B
79617-1	BPS Bioscience	100 ml	EUR 135
Description: This liquid Assay Medium is optimized for use in cellular assays in select BPS Bioscience's cell lines, including:_x000D_• TGF/SMAD Signaling Pathway SBE Reporter - HEK293 Cell Line #60653 _x000D_• AP-1 Reporter - HEK293 Recombinant Cell Line (JNK signaling pathway) #60405

Assay Medium 1B
79617-2	BPS Bioscience	500 ml	EUR 675
Description: This liquid assay medium is optimized for use in cellular assays in select BPS Bioscience's cell lines, including:_x000D_• TGF/SMAD Signaling Pathway SBE Reporter - HEK293 Cell Line #60653 _x000D_• AP-1 Reporter - HEK293 Recombinant Cell Line (JNK signaling pathway) #60405

Assay Medium 2B
79619-1	BPS Bioscience	100 ml	EUR 120
Description: This liquid assay medium is optimized for use in cellular assays in select BPS Bioscience's cell lines, including:_x000D_• Foxp3 Reporter (Luc) - Jurkat Recombinant Cell Line -#60628

Assay Medium 2B
79619-2	BPS Bioscience	500 ml	EUR 600
Description: This liquid assay medium is optimized for use in cellular assays in select BPS Bioscience's cell lines, including:_x000D_• Foxp3 Reporter (Luc) - Jurkat Recombinant Cell Line -#60628

Assay Medium 5A
79620-1	BPS Bioscience	100 ml	EUR 120
Description: This liquid Assay Medium is optimized for use in cellular assays in select BPS Bioscience cell lines.

Assay Medium 5A
79620-2	BPS Bioscience	500 ml	EUR 600
Description: This liquid Assay Medium is optimized for use in cellular assays in select BPS Bioscience cell lines.

Assay Medium 2A
79621-1	BPS Bioscience	100 ml	EUR 120
Description: This liquid Assay Medium is optimized for use in cellular assays in select BPS Bioscience's cell lines, including:_x000D_• ADCC Bioassay Effector Cell F variant (Low Affinity) - Jurkat Recombinant Cell Line #60540 _x000D_• ADCC Bioassay Effector Cell V variant (High Affinity) - Jurkat Recombinant Cell Line #60541

Assay Medium 2A
79621-2	BPS Bioscience	500 ml	EUR 600
Description: This liquid Assay Medium is optimized for use in cellular assays in select BPS Bioscience's cell lines, including:_x000D_• ADCC Bioassay Effector Cell F variant (Low Affinity) - Jurkat Recombinant Cell Line #60540 _x000D_• ADCC Bioassay Effector Cell V variant (High Affinity) - Jurkat Recombinant Cell Line #60541

Assay Medium 2C
79623-1	BPS Bioscience	100 ml	EUR 120
Description: This liquid assay medium is optimized for use in cellular assays in select BPS Bioscience's cell lines, including:_x000D_• TIGIT / NFAT Reporter - Jurkat Recombinant Cell Line - #60538_x000D_• CD155/TCR Activator - CHO Recombinant Cell Line -#60548

Assay Medium 2C
79623-2	BPS Bioscience	500 ml	EUR 600
Description: This liquid assay medium is optimized for use in cellular assays in select BPS Bioscience's cell lines, including:_x000D_• TIGIT / NFAT Reporter - Jurkat Recombinant Cell Line, #60538 • CD155/TCR Activator - CHO Recombinant Cell Line, #60548

Assay Medium 7B
79718-1	BPS Bioscience	100 ml	EUR 120
Description: This liquid assay medium is optimized for use in cellular assays in select BPS Bioscience cell lines._x000D_Optimized for use with Myc Reporter (Luc) - HCT116 Recombinant Cell Line (Myc Signaling Pathway), #60520

Assay Medium 7B
79718-2	BPS Bioscience	500 ml	EUR 600
Description: This liquid assay medium is optimized for use in cellular assays in select BPS Bioscience cell lines._x000D_Optimized for use with Myc Reporter (Luc) - HCT116 Recombinant Cell Line (Myc Signaling Pathway), #60520

Assay Medium 1A
79805-1	BPS Bioscience	100 ml	EUR 120
Description: This liquid Assay Medium is optimized for use in cellular assays in select BPS Bioscience's cell lines, including TrkA / SRE Reporter - HEK293 Recombinant Cell Line (#79798)

Assay Medium 1A
79805-2	BPS Bioscience	500 ml	EUR 600
Description: This liquid Assay Medium is optimized for use in cellular assays in select BPS Bioscience's cell lines, including TrkA / SRE Reporter - HEK293 Recombinant Cell Line (#79798)

Assay Medium 2C
78544-1	BPS Bioscience	100 ml	EUR 120
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines.

Assay Medium 2C
78544-2	BPS Bioscience	500 ml	EUR 600
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines.

Assay Medium 7A
78673-1	BPS Bioscience	100 ml	EUR 120
Description: This liquid Assay Medium is optimized for use with BPS Bioscience cell-based assay

Assay Medium 7A
78673-2	BPS Bioscience	500 ml	EUR 600
Description: This liquid Assay Medium is optimized for use with BPS Bioscience cell-based assay

Assay Medium 1C
78674-1	BPS Bioscience	100 ml	EUR 120
Description: This liquid Assay Medium is optimized for use with BPS Bioscience cell-based assay.

Assay Medium 1C
78674-2	BPS Bioscience	500 ml	EUR 600
Description: This liquid Assay Medium is optimized for use with BPS Bioscience cell-based assay.

H Medium Broth
DJ1019	Bio Basic	100g	EUR 73.06

OF BASAL MEDIUM
O15-100-10kg	Alphabiosciences	10 kg	Ask for price

OF BASAL MEDIUM
O15-100-2kg	Alphabiosciences	2kg	Ask for price

OF BASAL MEDIUM
O15-100-500g	Alphabiosciences	500 g	Ask for price

NeuroProgenitor Medium
NM42400	Neuromics	125 ml	EUR 364.8

Growth Medium 3A
60188	BPS Bioscience	500 ml	EUR 755
Description: This liquid Growth Medium is a complete medium optimized to culture select CHO and CHO-K1 cell lines.

Growth Medium 2A
60190	BPS Bioscience	500 ml	EUR 755
Description: This liquid Growth Medium is a complete medium optimized to culture select Jurkat cell lines.

Growth Medium 3K
78041	BPS Bioscience	500 ml	EUR 650
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines. _x000D_Optimized for Use With_x000D_ CD19 / BCMA / Firefly Luciferase - CHO Recombinant Cell Line (BPS Bioscience, #78030)

Growth Medium 7C
78076	BPS Bioscience	500 ml	EUR 650
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell pools_x000D_Optimized for use With: Cas9-expressing HCT116 cell pool (BPS Bioscience, #78073)

Growth Medium 6C
78077	BPS Bioscience	500 ml	EUR 650
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell pools._x000D_Optimized for use with: Cas9-expressing A549 cell pool (BPS Bioscience, #78072)

Growth Medium 2K
78078	BPS Bioscience	500 ml	EUR 650
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell pools._x000D_Optimized for use with: Cas9-expressing Jurkat cell pool (BPS Bioscience, #78070) Cas9-expressing Raji cell pool (BPS Bioscience, #78071)

Growth Medium 2L
78094	BPS Bioscience	500 ml	EUR 650
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell pools._x000D_Optimized for Use With: CRISPRa (SAM) Jurkat Cell Pool (BPS Bioscience, #78080)

Growth Medium 1P
78095	BPS Bioscience	500 ml	EUR 685
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines._x000D_Optimized for Use With:_x000D_ TMPRSS2 - Vero E6 Recombinant Cell Line (BPS Bioscience, #78081)

Growth Medium 1Q
78096	BPS Bioscience	500 ml	EUR 650
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell pools_x000D_Optimized for Use With:_x000D_ Cas9-Expressing Neuro2A Cell Pool (BPS Bioscience, #78087)

Growth Medium 3L
78104	BPS Bioscience	500 ml	EUR 650
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines.

Growth Medium 1R
78180	BPS Bioscience	500 ml	EUR 650
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell pools.Optimized for Use With: Cas9-Expressing MCF7 Cell Pool (BPS Bioscience #78179)

Growth Medium 2M
78181	BPS Bioscience	500 ml	EUR 650
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines.

Growth Medium 2N
78196	BPS Bioscience	500 ml	EUR 650
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines.

Growth Medium 7D
78200	BPS Bioscience	500 ml	EUR 650
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines

Growth Medium 1S
78221	BPS Bioscience	500 ml	EUR 650
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines.Optimized for Use With: CRISPRa (SAM) HeLa Cell Line (BPS Bioscience, #78193), CRISPRa (SAM) HepG2 Cell Line (BPS Bioscience, #78194)

Growth Medium 6D
78222	BPS Bioscience	500 ml	EUR 650
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines.Optimized for Use With: CRISPRa (SAM) HEK293 Cell Line (BPS Bioscience, #78192)

Growth Medium 2P
78354	BPS Bioscience	500 ml	EUR 650
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines.

Growth Medium 3M
78377	BPS Bioscience	500 ml	EUR 650
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines.

Growth Medium 1T
78379	BPS Bioscience	500 ml	EUR 650
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines.

Growth Medium 2Q
78380	BPS Bioscience	500 ml	EUR 650
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines.

Growth Medium 6E
78385	BPS Bioscience	500 ml	EUR 650
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines.

Growth Medium 1A
79528	BPS Bioscience	500 ml	EUR 715
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines. Follow the culturing instructions on the designated protocol.

Growth Medium 3B
79529	BPS Bioscience	500 ml	EUR 715
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines. Follow the culturing instructions on the designated protocol.

Growth Medium 2B
79530	BPS Bioscience	500 ml	EUR 700
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines. Follow the culturing instructions on the designated protocol._x000D_Optimized for use with:_x000D_IL-2 Jurkat Luciferase Reporter - Jurkat Cell Line #60481 NF-kB Luciferase Reporter - Jurkat Cell Line #60651 Foxp3 Reporter (Luc) - Jurkat Recombinant Cell Line #60628

Growth Medium 1B
79531	BPS Bioscience	500 ml	EUR 755
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines. Follow the culturing instructions on the designated protocol.

Growth Medium 1C
79532	BPS Bioscience	500 ml	EUR 755
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines. Follow the culturing instructions on the designated protocol.

Growth Medium 1K
79533	BPS Bioscience	500 ml	EUR 715
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines. Follow the culturing instructions on the designated protocol.

Growth Medium 5A
79534	BPS Bioscience	500 ml	EUR 715
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines. Follow the culturing instructions on the designated protocol.

Growth Medium 4A
79535	BPS Bioscience	500 ml	EUR 650
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines. Follow the culturing instructions on the designated protocol.

Growth Medium 1D
79536	BPS Bioscience	500 ml	EUR 650
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines. Follow the culturing instructions on the designated protocol.

Growth Medium 3C
79537	BPS Bioscience	500 ml	EUR 650
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines. Follow the culturing instructions on the designated protocol.

Growth Medium 1E
79538	BPS Bioscience	500 ml	EUR 650
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines. Follow the culturing instructions on the designated protocol.

Growth Medium 3D
79539	BPS Bioscience	500 ml	EUR 735
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines. Follow the culturing instructions on the designated protocol.

Growth Medium 1F
79540	BPS Bioscience	500 ml	EUR 755
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines. Follow the culturing instructions on the designated protocol.

Growth Medium 5B
79541	BPS Bioscience	500 ml	EUR 685
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines. Follow the culturing instructions on the designated protocol.

Growth Medium 6A
79542	BPS Bioscience	500 ml	EUR 650
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines.

Growth Medium 7A
79543	BPS Bioscience	500 ml	EUR 650
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines.

Growth Medium 1G
79544	BPS Bioscience	500 ml	EUR 755
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines. Optimized for use with GR-GAL4 Reporter (Luc) -HEK293 Recombinant Cell Line (Glucocorticoid Receptor Pathway), #60655, and CD137/NF-κB Reporter - HEK293 Recombinant Cell Line, #79289

Growth Medium 7B
79545	BPS Bioscience	500 ml	EUR 650
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines._x000D_Optimized for use with Myc Reporter (Luc) - HCT116 Recombinant Cell Line, #60520.

Growth Medium 1H
79546	BPS Bioscience	500 ml	EUR 650
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines.Optimized for Use With: T-Rex HEK293 Recombinant Cell Line (BPS Bioscience, #71227)

Growth Medium 1J
79552	BPS Bioscience	500 ml	EUR 650
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines.

Growth Medium 3E
79553	BPS Bioscience	500 ml	EUR 650
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines.

Growth Medium 4B
79554	BPS Bioscience	500 ml	EUR 650
Description: This liquid Growth Medium is optimized for use in cellular assays in select BPS Bioscience's cell lines, including: • Nav1.8/β2 - HEK293 Recombinant Cell Line #60521

Growth Medium 1L
79555	BPS Bioscience	500 ml	EUR 650
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines.

Growth Medium 2C
79592	BPS Bioscience	500 ml	EUR 650
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines. Follow the culturing instructions on the designated protocol._x000D_Optimized for use with:_x000D_ GITR/NF-κB Luciferase Reporter (Luc) - Jurkat Cell Line #60546_x000D_

Growth Medium 4C
79631	BPS Bioscience	500 ml	EUR 650
Description: This liquid Growth Medium is optimized for use in cellular assays in select BPS Bioscience's cell lines, including: • CFTR - HEK 293 Recombinant Cell Line - #60506

Growth Medium 2E
79638	BPS Bioscience	500 ml	EUR 715
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines. Follow the culturing instructions on the designated protocol._x000D_Optimized for use with:_x000D_CRE/CREB Reporter (Luc) - Jurkat Cell Line - #79636_x000D_

Growth Medium 2D
79639	BPS Bioscience	500 ml	EUR 650
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines.Optimized for Use With: TCR Activator - Raji Cell Line (BPS Bioscience, #60556)

Growth Medium 8A
79653	BPS Bioscience	500 ml	EUR 650
Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines. Follow the culturing instructions on the designated protocol._x000D_Optimized for Use With: _x000D_NF- κB Reporter (Luc) - THP-1 Cell Line - #79645

ligand recognition at the human leukotriene B4 receptor 1

Reverse alterations of 5-HT 2A receptor mind density in topics with schizophrenia: relevance of radiotracers pharmacological profile

κ-opioid receptor stimulation alleviates rat vascular easy muscle cell calcification through PFKFB3-lactate signaling

BSA-drug-ZnO-PEI conjugates interplay with glycans of gp60 endothelial cell receptor protein for focused drug supply: a complete spectroscopic research

EC MEDIUM

EC MEDIUM

EC MEDIUM

OF Medium

M9 Medium

YM Medium

HLP MEDIUM

HLP MEDIUM

HLP MEDIUM

M63 Medium

SIM MEDIUM

SIM MEDIUM

SIM MEDIUM

SOB MEDIUM

SOB MEDIUM

SOB MEDIUM

Ec Medium 500gm

TCBS Medium

M9CA Medium

Sob Medium 500gm

Rat Cartilage Growth Medium PrimaCell: Normal Articular Cartilage Growth Medium

DNase Medium

TYGPN Medium

Heller's Medium

Heller's Medium

Human Cartilage Growth Medium PrimaCell: Normal Articular Cartilage Growth Medium

Insect Cell Medium: TNM-FH Insect Culture Medium

Mounting Medium

Advanced Medium

COLIFORM MEDIUM

COLIFORM MEDIUM

COLIFORM MEDIUM

Hoagland's Medium

Hoagland's Medium

Insect Cell Medium: Serum-Free Insect Culture Medium

RPMI 1640 Medium

A-1 MEDIUM

A-1 MEDIUM

A-1 MEDIUM

MCDB 131 Medium

MCDB 131 Medium

MCDB 131 Medium

MCDB 131 Medium

MCDB 131 Medium

Medium 199/BCDB 105

Insect Cell Medium: Grace?s Insect Medium (Unsupplemented)

Isp Medium 2 500gm

Isp Medium 4 500gm

BPS Medium 1

BPS Medium 7

BPS Medium 8

Thaw Medium 4

Thaw Medium 4

Thaw Medium 5

Thaw Medium 5

Thaw Medium 6

Thaw Medium 6

Thaw Medium 2

Thaw Medium 2

Thaw Medium 7

Thaw Medium 7

Thaw Medium 3

Thaw Medium 3

Thaw Medium 1

Thaw Medium 1

10mL S.O.C. Medium

Thaw Medium 12

Thaw Medium 12

Thaw Medium 14

Thaw Medium 14

Thaw Medium 8

Thaw Medium 8

Thaw Medium 9

Thaw Medium 9

Thaw Medium 10

Thaw Medium 10

Reverse alterations of 5-HT _2A receptor mind density in topics with schizophrenia: relevance of radiotracers pharmacological profile